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Absolute Contraindications to Thrombolytic Administration

hi my name is Paul John and for today's

hippo short we're gonna go over a simple

memory tool to cover the absolute

contradict Asians to thrombolytic

administration in acute ischemic stroke

presenting within three hours now from

institution to institution the exclusion

criteria vary slightly

and so you should refer to your

institutional protocol however we're

going to be covering the 2016

eh-eh-eh-eh SI guidelines and consists

of one question followed by the letters

A through G the question is is this a

bleed like most institutional protocols

you get a non-contrast head CT to look

for the obvious intracranial hemorrhage

but don't forget suspected subarachnoid

hemorrhage is an absolute

contraindication is for AV malformation

or aneurysm or any intracranial neoplasm

for that matter

B is for blood pressure systolic greater

than 185 or diastolic greater than 110 C

is for CNS procedure or significant head

trauma or a recent stroke any of which

within the past three months

D is for diathesis that's bleeding

coagulopathy like platelets less than a

hundred thousand or inr greater than one

point seven while on warfarin or a PTT

that's elevated above normal while in

heparin or novel oral anticoagulants is

for endocarditis

whether it's confirmed or suspected

infective endocarditis F is for any

former history of intracranial

hemorrhage at any point in time and G is

for glucose less than 50 or greater than

400 and that's your memory tool for

remembering the absolute convocations to

thrombolytic administration in acute

ischemic stroke presenting within three

hours if you want more information on

this topic head on over to hippo

education com my name is Paul John I'll

see you next time

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